产品类别
兔抗人、大、小鼠肾上腺髓质素抗体
产品价格
0.1ml/480元 0.2ml/800元
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
肾上腺髓质素(Adrenomedullin, AM)是广泛分布在肾上腺髓质、肺、心、肝、肾等器官。
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. mol wt:20kDa Other Aliases: Adrenomedullin; ADM; ADM precursor; PAMP; Preproadrenomedullin; Proadrenomedullin N20 terminal peptide; ProAM N terminal 20 peptide; ProAM N20; ProAMN20.
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