产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

    CCL1属于CC趋化因子家族，是由活化的T细胞分泌的糖蛋白。CCL1是一小分子的细胞因子C与细胞表面的趋化因子受体CCR8结合,对单核细胞，自然杀伤细胞，未成熟的B细胞和树突状细胞有细胞趋化作用.
    I-309 is a member of the C-C, or beta chemokine class. Other chemokines in this group include MIP1 alpha, MIP1 beta, RANTES, MCP1/2/3/4, mouse JE, 1 - 2 µg/ml antibody detects 20 and mouse MARC, eotaxin, HCC1 and C10. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. I-309 was originally identified by subtractive hybridization as a transcript that was present in a gamma/delta T cell line but not in EBVtransformed B cells. I-309 is a chemoattractant for monocytes, but not for neutrophils. IP-10 is an approximately 8.5 kD polypeptide of 73 amino acids. The precursor form of human I-309 consists of 96 amino acids. To generate the mature I-309, the precursor cleaves its hydrophobic signal peptide. Human I-309 is thought to be a homologue of the mouse TCA3, and shows 42% amino acid homology to mouse TCA3.
    mol wt:10kDa
    Other Aliases:
    C-C motif chemokine 1 precursor; chemokine (C-C motif) ligand 1; BF534335; I-309; Scya1; CCL1; Chemokine CC Motif Ligand 1; inflammatory cytokine I-309; P500; SCYA1; SISe; small inducible cytokine A1; T lymphocyte secreted protein I-309; TCA3