产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77% and 70% amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated. mol wt:10kDa Other Aliases: Macrophage Inflammatory Protein 1 alpha; AI323804; G0S19-1; LD78 alpha; MIP-1alpha; MIP1-(a); MIP1-alpha; Mip1a; Scya3; SCYA 3;Tonsillar lymphocyte LD78 alpha protein; CCL 3; Chemokine C C motif ligand 3; G0/G1 switch regulatory protein 19 1; G0S19 1; G0S19 1 protein; Heparin binding chemotaxis protein ; L2G25B ; LD78ALPHA; PAT 464.1; SIS alpha; SIS beta; Small inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein
|