产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
衰变加速因子(CD55)是血细胞膜上糖化磷脂酰肌醇(GPI)锚定蛋白,具有抑制补体系统激活,参与信号传递,有协助T淋巴细胞活化功能. This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. Alternative names: CD55; DAF; CD55 Cromer blood group system; CD55 molecule; Complement decay accelerating factor; CR; Cromer Blood Group antigen; Cromer blood group system; DAF; Decay Accelerating Factor for Complement; TC
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