产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
Neuronal Marker NCAM-L1又称L1细胞粘附分子(L1CAM)是一种细胞表面糖蛋白,属于免疫球蛋白超家族的神经细胞粘附分子家族。L1CAM可能在神经系统发育过程中发挥作用。 L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]. mol wt:138kDa Other Aliases: L1 cell adhesion molecule isoform 1 precursor; L1cam; Neural cell adhesion molecule ligand 1; CD171; L1CAM; CAML1; HSAS; HSAS1; MASA; MIC5; L1; L1-NCAM; NCAM-L1
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