产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
CIB1是通过抑制eurekalert AK1(p21蛋白激酶)来发挥作用的。当CIB1激活PAK1后,会促发一系列蛋白磷酸化,从而抑制细胞迁移.CIB1在抑制肿瘤转移中有很重要的作用.
CIB1(Calcium and integrin binding 1) may convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through the binding to the integrin cytoplasmic domain. mol wt:21kDa Other Aliases: Cib; Sip2-28; Cibkip; Kip; Prkdcip
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