产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
结构蛋白(Structural Proteins) 细胞角蛋白常用于肿瘤细胞的分化、增殖及转移方面的研究。有学者认为:在肿瘤细胞分化过程中有细胞角蛋白的表达,把细胞角蛋白作为肿瘤干细胞的标志物。阳性部位:主要在胞浆。
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]. mol wt:73kDa Other Aliases: 67 kDa cytokeratin; CK1; Cytokeratin 1/19/8; EHK1; Hair Alpha Protein; Keratin 1/19/8; Keratin Type II Cytoskeletal 1; KRT1; KRT19; KRT1A; KRT8; KRTA; K 1; K1; Keratin 1
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