产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

细胞色素3A4(CYP3A4)是细胞色素P450 超家族成员之一, 主要存在于肝脏中和小肠中。它是人类药物代谢酶中的最重要的酶, CYP3A4与外源性致癌物、抗癌药物和内源性类固醇激素、维生素、脂肪酸的代谢转化密切相关。
Cytochromes P450 are a group of heme thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8 oxidation, omeprazole sulphoxidation, midazolam 1 hydroxylation and midazolam 4 hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.

Also known as:

CP33
CP34
CYP3A
CYP3A3
CYP3A4
CYPIIIA4
Cytochrome P450 family 3 subfamily A polypeptide 4
Cytochrome P450 subfamily IIIA polypeptide 4
Glucocorticoid inducible P450
HLP
MGC126680
NF 25
NF25
P450 III steroid inducible
P450 PCN1
P450C3
P450PCN1
Quinine 3 monooxygenase
Taurochenodeoxycholate 6 alpha hydroxylase