产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
    mol wt:54kDa
    Other Aliases:
    Cytochrome P450 21; cytochrome P450, family 21, subfamily A, polypeptide 2; 21-OH, 21OHA, 21OHB, CA21H, CAH1, CHOLESTEROL 21-HYDROXYLASE, CPS1, CYP21, Cyp21-ps1, Cyp21a1, CYP21A2, Cyp21a2-ps, CYP21B, CYP21OH-A, MGC150536, MGC150537, MGC156449, Oh21-1, Oh21-2, P450C21, P450c21B