产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
高半胱氨酸蛋白61是富含半胱氨酸的分泌性肝素连接蛋白,是CCN家族成员之一,属于生长因子诱导的即刻早期基因,有明显的促有丝分裂和趋化活性作用,有诱导成纤维细胞增殖和分泌细胞外基质等功能,可促进细胞增殖、迁移、黏附、分化和细胞外基质(ECM)合成的作用,在新生血管及肿瘤形成过程中起着重要作用。
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor-inducible immediate-early gene. Acting as an extracellular, matrix-associated signaling molecule, CYR61 promotes the adhesion of endothelial cells through interaction with integrin and augments growth factor-induced DNA synthesis in the same cell type. mol wt:42kDa Other Aliases: cysteine rich protein 61; 3CH61; CCN 1; CCN1; CYR 61; CYR61; CYR61 protein; CYR61 protein precursor; Cysteine rich angiogenic inducer 61; Cysteine rich heparin binding protein 61; GIG 1; GIG1; GIG1; Igfbp 10; IGFBP10; Insulin like growth factor binding protein 10; Protein CYR61; Protein GIG1; AI325051
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