产品类别

 兔抗人、大、小鼠GCK抗体

产品价格

 0.2ml/890元  

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 

产品介绍

 Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of this gene results in three tissue specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose 6 phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non insulin dependent diabetes mellitus, also called maturity onset diabetes of the young, type 2; mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
 mol wt:51kDa
 Other Aliases:
 Glucokinase; ATP D hexose 6 phosphotransferase; GCK; GK; GLK; Glucokinase isoform 1; Hexokinase 4; Hexokinase D; Hexokinase D pancreatic isozyme; Hexokinase type IV; Hexokinase4; HexokinaseD; HHF 3; HHF3; HK 4; HK IV; HK4; HXKP; Maturity onset diabetes of the young 2; MODY 2; MODY2; GLUKA; RNGK2.