产品类别

 兔抗人、大、小鼠GlyR alpha 1/2/3抗体

产品价格

 0.2ml/890元  

产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

 WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 

产品介绍

   甘氨酸受体alph a1是中枢神经系统中的重要抑制性离子通道受体，是哺乳类中枢神经系统中神经递质受体蛋白，属于配体门控离子通道超家族成员.
   Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
    mol wt:49kDa
    Other Aliases:
    glycine receptor α1; GLRA1; GLRA2; Glycine receptor 48 kDa subunit; Glycine receptor alpha 1; Glycine receptor alpha 2; Glycine receptor subunit alpha 1; Glycine receptor subunit alpha 2; Glycine receptor, alpha 1 subunit; Glycine receptor, alpha 2 subunit; MGC138878; MGC138879; STHE