产品类别
兔抗人、大、小鼠Granzyme A抗体
产品价格
0.2ml/1480元
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
GzmA是存在于细胞毒性T淋巴细胞(CTL)和自然杀伤细胞(NK细胞)的细胞毒颗粒中含量最多的一种丝氨酸蛋白酶。 Granzyme A is the most abundant of the proteases occurring in CTL granules. It is homologous to other serine esterases, including other granyzmes, mast cell proteases, and neutrophil cathepsins. Granzyme A is unique among granzymes in that it is a disulfide linked homodimer. Granzyme B is thought to be a rapidly acting apoptotic enzyme, while Granzyme A is thought to be slow acting. Granzyme A is a 28 kD protein
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