产品类别
兔抗人、大、小鼠组蛋白H2AX抗体
产品价格
0.2ml/1480元
产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
H2AX蛋白属于组蛋白一族,组蛋白参与细胞内DNA的组合、包装. Histone H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. Histone H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double strand breaks is the phosphorylation of Histone H2A.X at serine 139 at the sites of DNA damage
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