生产产地
美国sigma公司产品
产品类别
蛋白
产品标准
纯度≥90%
产品应用
分子生物学、免疫学等
产品介绍
美国sigma公司产品,原货号:T1001。
Thyroglobulin from bovine thyroid powder, ≥90% (agarose gel electrophoresis) Bovine thyroglobulin is a large, tetrameric glycoprotein produced in the thyroid gland as a precursor to thyroid hormones. Its large size and absence from plasma under normal conditions makes it very immunogenic and reduces the chance that antibodies to this carrier protein will cross-react with plasma proteins in immunoassays. Haptens may be conjugated to thyroglobulin via accessible secondary amines. Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Properties
assay |
≥90% (agarose gel electrophoresis) |
form |
powder |
mol wt |
mol wt -670 kDa |
composition |
Iodine, ≥0.25% |
nitrogen analysis |
13.0-16.0% total |
ash |
≤4% |
color |
white to tan |
solubility |
H2O: 20 mg/mL |
storage temp. |
−20°C |
|