产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

 

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 

产品介绍

    VASH1是一个内皮组织衍生的可被血管内皮生长因子诱导的分泌性蛋白质,它是目前为止发现的唯一以负反馈为作用机制调节血管新生的因子。它的发现证实在血管新生的过程中也存在经典的自身调节控制机制—负反馈调节机制的存在。

    VASH1 is a angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. It does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis and acts in an autocrine manner. VASH1 also inhibits artery neointimal formation and macrophage infiltration and exhibits heparin-binding activity. There are two named isoforms.
    mol wt:41kDa
    Other Aliases:
    Vasohibin 1; KIAA1036; VASH