产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
产品介绍
Trop-2蛋白主要存在于细胞胞质及表面, 它是丝裂原活化蛋白激酶(MAPK)通路的一个重要组成部，参与细胞生长、增殖、分化、死亡及细胞间的功能同步等多种生理过程.
Trop-2在很多常见的肿瘤上扮演着重要角色，其中包括乳腺癌、胃癌、结肠癌、肺癌、前列腺癌、胰腺癌和子宫癌，有学者认为：Trop-2在孕期內所具有的生殖功能可能意味著它同肿瘤的生长有关联。
tropomyosin 2, beta (Trop-2 /gp50/ Tpm2) is a dimeric coiled coil protein that binds along the length of actin filaments. It is associated with the thin filaments of muscle cells and the microfilaments of nonmuscle cells. Chicken embryo fibroblasts (CEF) contain five isoforms of tropomyosin (a, b, 1, 2, and 3), identified as such by their different apparent molecular masses after separation by SDS-PAGE, but similar biochemical properties, such as resistance to heat and organic solvents, the ability to bind to F actin filaments, and the lack of proline and tryptophan
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