产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）
产品介绍
SPA 1是重要的Rap1GTP酶激活蛋白.SPA-1参与细胞的程序性死亡，在很多恶性肿瘤的发生、发展中起到一定的作用。
[FUNCTION] GTPase activator for the nuclear Ras-related regulatory protein Rap1, Rsr1 and Ran in vitro, converting it to the putatively inactive GDP-bound state. Affects cell cycle progression.
[SUBCELLULAR LOCATION] Nucleus. Note=Mostly nuclear.
[TISSUE SPECIFICITY] Preferentially expressed in both fetal and adult lymphohematopoietic tissues.
[INDUCTION] By mitogens.
[SIMILARITY] Contains 1 PDZ (DHR) domain.
[SIMILARITY] Contains 1 Rap-GAP domain.
[SEQUENCE CAUTION] Sequence=BAA01973.1; Type=Frameshift; Positions=Several
|
