产品标准

 浓缩液(1mg/1ml) 亲和纯化抗体

 

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

 

产品介绍

    是一种连接G-蛋白的受体,主要分布在脑和胰腺。目前有学者用于肿瘤方面的研究。

    Somatostatin is a tetradecapeptide that is widely distributed in the body. It acts on multiple organs in the body and also functions as a neuropeptide affecting electrical activity of neurons. Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues.
    There are five somatostatin receptor subtypes termed SSTR 1 to 5. They are G protein coupled receptors characterized by seven transmembrane helices with an extracellular amino terminal domain and an intracellular carboxy terminus. These receptors are activated by somatostatin secreted by nerve and endocrine cells and function in the regulation of numerous physiological processes such as the secretion of insulin, glucagon and growth hormone. The SSTRs also play a role in cell growth induced by neuronal excitation in both the central and peripheral nervous system. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
    mol wt:46kDa
    Other Aliases:
    somatostatin receptor 3; OTTHUMP00000028737; Smstr3; Somatostatin receptor 3; Somatostatin receptor subtype 3; Somatostatin receptor type 3; SS3R; SSR28; Sst3; SSTR 3; SSTR3