产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

    WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍SEL1L, highly similar to the C elegans sel-1 gene, is a recently cloned human gene whose function is under investigation. SEL1L is differentially expressed in tumors and normal tissues and seems to play a role in tumor growth and aggressiveness. It may be an important negative regulator of the "notch" pathway which acts as a key regulator of the cellular proliferation and specification processes in both vertebrates and invertebrates. SEL1L may function in the protein degradation processes through the ubiquitin-proteosome system and perhaps in regulating important pathways such TGF-beta.
    It is ubiquitously expressed only in fetal and neoplastic tissues. In normal adult tissues is highly expressed in the acini and in the alpha cells of the pancreas; in general it is highly represented in secretory cells such as plasma cells.
    mol wt:88kDa
    Other Aliases:
    Suppressor of lin-12-like Protein; IBD2; PRO1063; Sel 1 like protein; Sel 1 suppressor of lin 12 like; SEL1 LIKE; SEL1LIKE; TSA305; AW493766; KIAA4137; mKIAA4137; Sel1h; Sel1l