产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

The Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer.
mol wt:28kDa
Other Aliases:
peroxiredoxin 3; Antioxidant Protein 1; AOP 1; AOP1; HBC189; MER 5; MER5; MGC104387; MGC24293; Mitochondrial thioredoxin dependent peroxide reductase; Peroxiredoxin3; PRDX 3; PRDX3; PRO1748; Protein MER5 homolog; PRX III; PRX3; SP 22; SP22; Thioredoxin dependent peroxide reductase mitochondrial; Thioredoxin dependent peroxide reductase precursor