产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

    Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex (By similarity).
    mol wt:55kDa
    Other Aliases:
    Proline hydrolase 4; proline 4-hydroxylase; P4htm; hypoxia-inducible factor prolyl 4-hydroxylase; Transmembrane prolyl 4-hydroxylase; P4H-TM; HIF-prolyl hydroxylase PH-4