产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
生长因子和激素( Growth Factor and Hormones) 血小板源性生长因子(PDGF),是由A、B两条多肽链通过二硫键连接而成的同型或异型二聚体。包括三种形式:PDGF-AA、PDGF-BB、PDGF-AB.分子量为28~35KD。 PDGF-BB也是PDGF家族成员,是一种碱性蛋白,可促进细胞分裂并促进神经元的生长, PDGF-BB的正常表达对于神经系统的发育和成熟起着一定的作用。
Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis. mol wt:54kDa Other Aliases: platelet derived growth factor-BB; Becaplermin; C sis; FLJ12858; Oncogene SIS; PDG B chain; PDGB; PDGF 2; PDGF B; PDGF B chain; PDGF2; PDGFB; PDGFB/COL1A1 fusion gene; Platelet derived growth factor 2; Platelet derived growth factor B chain; Platelet derived growth factor beta; Platelet derived growth factor beta polypeptide; Simian sarcoma viral (v sis) oncogene homolog; SIS; SSV; V sis platelet derived growth factor beta polypeptide
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