产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
PEA3属癌基因的转录因子Ets家族成员之一,多定位于细胞核。
Pea3 is a member of the Ets gene family which are known to encode sequence specific DNA binding proteins. Pea3 binds the motif 5-AGGAAG-3 (the Pea-3 motif). It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. Pea3 is detected in cells of epithelial and fibroblastic origin. It is also an transcriptional activator that binds to the enhancer of the adenovirus E1A gene. mol wt:53kDa (human, rat) 61kDa (mo) Other Aliases: polymoma virus enhancer 3; ETV4; ets variant 4; ets; E1A-F; E1AF; PEA3; PEAS3
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