产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
P2Y1 receptor 为离子通道蛋白,一种受体配体开启的离子通道,介导细胞外核苷酸细胞间信号传导。 P2Y1 belongs to the family of G-protein coupled receptors, and functions as a receptor for extracellular ATP and ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. [SUBCELLULAR LOCATION] Cell membrane; Multi-pass membrane protein. [TISSUE SPECIFICITY] Expressed in muscle, heart, liver, kidney, lung, brain, spleen, but not in testis. [SIMILARITY] Belongs to the G-protein coupled receptor 1 family.
Also known as: ATP receptor; P2 purinoceptor subtype Y1; P2RY1; P2Y purinoceptor 1; P2Y1 purinoceptor; Platelet ADP receptor; Purinergic receptor; Purinergic receptor P2Y G protein coupled 1; Purinergic receptor P2Y1
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