产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500    （石蜡切片需做抗原修复）

产品介绍

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8 / JNK1, MAPK9 / JNK2, and MAPK14 / p38, but not MAPK1 / ERK2 or MAPK3 / ERK3. This kinase is phosphorylated, and thus activated by MAP3K1 / MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
mol wt:44kDa
Other Aliases:
MAP Kinase Kinase 4; mitogen-activated protein kinase kinase 4; MAP2K4; JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SEK1; SERK1; Dual specificity mitogen-activated protein kinase kinase 4; MAPK/ERK kinase 4; MEK 4; JNK-activating kinase 1; c-Jun N-terminal kinase kinase 1; SAPK/ERK kinase 1; SEK1