产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
[FUNCTION] Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle. [SUBUNIT] Homodimer. [SUBCELLULAR LOCATION] Cytoplasm. [TISSUE SPECIFICITY] Detected in fetal brain (at protein level). Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, prostate, spleen, thymus, prostate, testis, ovary, small intestine and colon. [SIMILARITY] Belongs to the UPF0012 family. mol wt:30kDa Other Aliases: Nitrilase family, member 2; Omega-amidase NIT2; Nitrilase homolog 2; 1190017B19Rik; D16ERTD502E; MGC111199; MGC124762; NIT2; RGD1310494; NIT2 protein
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