产品标准
浓缩液(1mg/1ml) 亲和纯化抗体
产品应用
WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 (石蜡切片需做抗原修复)
产品介绍
合成与降解(Synthesis and Degradation) MMP10主要用于一些恶性肿瘤,如乳腺癌、胃肠道癌、卵巢癌等与转移浸润的研究.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. mol wt:52kDa Other Aliases: matrix metalloproteinase 10; stromelysin 2; SL-2; STMY2; AV377895, MMP10
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